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dc:titleInhibitory effects of different medicinal plants on Candida albicans growth
dc:creatorTambur, Zoran
dc:creatorCenić Milošević, Desanka
dc:creatorMileusnić, Ivan
dc:creatorDoder, Radoje
dc:creatorMarjanović, Marjan
dc:creatorMiljković Selimović, Biljana
dc:creatorKulišić, Zoran
dc:creatorOpačić, Dolores
dc:subjectCandida albicans
dc:subjectantifungal activity
dc:subjectmedicinal plants
dc:subjectessential oils
dc:subjectethanolic plant extract
dc:subjectminimum inhibitory concentration
dc:subjectAesculus hippocastanum
dc:subjectHypericum perforatum
dc:subjectSalvia officinalis
dc:descriptionThe objective of this study was to evaluate the in vitro antifungal properties of ethanol extracts and essential oils of medicinal plants from Serbia against Candida albicans (C. albicans) ATCC 10231. Ethanol extracts of fifteen plants were investigated, and their effects were compared with those of three different essential oils. The sensitivity of C. albicans to all plants was tested by the agar dilution method. The assay plates were estimated to contain 300, 150, 75, and 37.5 µg/ml of active extracts and 100, 50, 25, and 12.5 µg/ml of active essential oils. Inocula were applied to agar surfaces, giving approximately 106 cfu/ml of C. albicans. No inhibitory effects were observed for ethanol extracts of Hypericum perforatum and Salvia officinalis (MIC > 300 µg/ml). The most effective were the ethanol extract of Aesculus hippocastanum (MIC = 37.5 µg/ml) and the essential oil of Satureja kitaibelii (MIC = 12.5 µg/ml). Other plants showed MIC from 25 to 300 µg/ml. As far as we know, the inhibitory effects of these medicinal plants against the reference strain of C. albicans have not been commonly investigated in our country. Although the essential oil of Satureja kitaibelii shows strong activity against C. albicans, these results need clinical evaluation..
dc:publisherPolish Society of Veterinary Sciences
dc:date2018
dc:typeinfo:eu-repo/semantics/article
dc:typeinfo:eu-repo/semantics/publishedVersion
dc:identifierhttps://stomatoloskifakultet.rs/nauka/publikacija/182
dc:identifierDOI 10.21521/mw.5995
dc:identifierISSN 0025-8628
dc:sourceMedycyna Weterynaryjna 74(7): 473-476
dc:languageen
dc:rightsinfo:eu-repo/semantics/closedAccess
dc:rightsSva prava zadržana