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dc:titleChemical Analysis and Antimicrobial Potential Assessment of Wild Laurel from the National Park Skadar Lake, Montenegro
dc:creatorBojović, Dragica
dc:creatorŠoškić, Miomir
dc:creatorŽugić, Ana
dc:creatorT. Milenković, Marina
dc:creatorLjumović, Iva
dc:creatorM. Tadić, Vanja
dc:subjectlaurel
dc:subjectessential oils
dc:subjectchemical composition
dc:subject1,8-cineole
dc:subjectα-terpinyl acetate
dc:subjectlinalool
dc:subjectantibacterial activity
dc:subjectantifungal activity
dc:subjectStaphylococcus aureus
dc:subjectEnterococcus faecalis
dc:subjectBacillus subtilis
dc:subjectCandida albicans
dc:subjectfatty oils
dc:subjectsesquiterpene lactones
dc:subjectmedicinal plants
dc:descriptionIn light of the increasing demand for laurel, driven by renewed interest in natural products and traditional medicinal usage of this plant, our study aimed to investigate the in vitro antimicrobial activity of essential oils from leaves and fruits of laurel (EOL and EOF, respectively) collected in the National Park Skadar Lake, Montenegro, as it related to their chemical composition, assessing the possibility of their usage in cosmetics and pharmaceuticals. Also, fatty oil from the remaining laurel fruit after EOF isolation was investigated as a possible source of bioactive compounds. The most abundant components in EOL and EOF were 1,8-cineol (35.1% and 33.3%, respectively) and α-terpinyl acetate (10.4% and 7.0%, respectively). Linalool (7.6%) was found in EOL, while α- pinene (5.8%) and β-elemene (5.7%) were present in significant amounts in EOF. Antibacterial and antifungal properties of EOL and EOF showed strong antibacterial activity against Staphylococcus aureus, Enterococcus faecalis, and Bacillus subtilis, and potent antifungal effects against Candida albicans, opening the door for their application as antimicrobial agents. Chemical analysis of fatty oil unexpectedly revealed prominent content of sesquiterpene lactone dehydrocostunolide and phenylpropanoid derivative (E)-2-hexyl-cinnamaldehyde (21% and 5%, respectively), suggesting further investigations of this waste material as the source of valuable compounds with proven health benefits.
dc:publisherMultidisciplinary Digital Publishing Institute
dc:date2025
dc:typeinfo:eu-repo/semantics/article
dc:typeinfo:eu-repo/semantics/publishedVersion
dc:identifierhttps://stomatoloskifakultet.rs/nauka/publikacija/889
dc:identifierDOI 10.3390/app15126741
dc:identifierISSN 2076-3417
dc:sourceApplied Sciences 15(12): 6741
dc:languageen
dc:rightsinfo:eu-repo/semantics/closedAccess
dc:rightsSva prava zadržana